GHORI
πŸ‡©πŸ‡ͺVitaminΒ·Humectant repairΒ·β„– 012

Panthenol (Provitamin B5)

D-Panthenol Β· Provitamin B5

The molecule that turns into Vitamin B5 the moment it hits your hair.

Region

Germany Β· pharmaceutical fermentation

Form

Viscous colourless liquid

Shelf

36 months in sealed formulas

Class

Vitamin

Key finding

β‰₯98%

Purity of pharmaceutical-grade D-panthenol

Effective dose Β· Effective 0.5%–5% in leave-in and rinse-off formulas.
01

The brief.

Origin

Fermented in a German pharmaceutical facility using non-GMO glucose. USP-grade, the same purity used in wound-healing ointments.

Extraction

Fermentation yields the D-isomer only β€” the L-isomer is biologically inert. Purified to >98% before formulation.

Sustainability

Fermentation-derived, no animal inputs. The German facility runs on 100% renewable electricity and reuses fermentation water 8Γ— per batch.

02

How it works.

Panthenol's hydroxyl groups form hydrogen bonds with ambient water molecules, drawing moisture into the cortex. Once inside, it converts to pantothenic acid (Vitamin B5), a cofactor in fatty-acid synthesis inside keratinocytes β€” the cells that build the cuticle. Result: softer, springier, less-static strands.

Delivers

  • 01Draws moisture from the air into the cortex β€” a true humectant
  • 02Converts to Vitamin B5 topically, supporting keratinocyte function
  • 03Adds noticeable slip, softness and elasticity
  • 04Reduces static and flyaways
03

Molecular signature.

The bio-active constituents that make Panthenol (Provitamin B5) work β€” with standardised percentages where measured by HPLC.

  • 01

    D-Panthenol

    Alcohol precursor to pantothenic acid β€” converts to the vitamin inside the strand.

  • 02

    Hydroxyl groups

    Bind water molecules from ambient humidity into the cortex.

04

Signal profile.

EVIDENCEPOTENCYSAFETYHERITAGESENSORYSOURCING

Six-axis assay

A living profile β€” the vectors that make Panthenol (Provitamin B5).

  • Evidence52

    1 peer-reviewed source

  • Potency98

    Standardised at β‰₯98%

  • Safety92

    Broad tolerance

  • Heritage79

    Documented across 3 traditions

  • Sensory58

    Vitamin profile

  • Sourcing78

    Traceable provenance

05

Heritage.

The record

Isolated in 1931 by Roger Williams and named for the Greek pantothen (from everywhere) because it appears in nearly every food. Its topical hair benefits were documented in the 1950s and it became the signature ingredient of the Pantene brand β€” named directly for the molecule.

Traditional use

None as an isolate β€” but B5-rich foods like liver, egg yolks and grains have been folk-medicine shine remedies globally.

Naturally found in

  • Whole grains, liver, egg yolks
  • Fermented biotechnologically for cosmetic and pharma use
  • One of the most-studied hair humectants on record
06

Field β†’ phial.

Every gram of Panthenol (Provitamin B5) passes five gates before it enters a Ghori formula. No shortcuts, no re-labels β€” the paper trail runs from soil to seal.

  1. π–€£01

    Stage 01

    Harvest

    Fermented in a German pharmaceutical facility using non-GMO glucose. USP-grade, the same purity used in wound-healing ointments.

  2. ❋02

    Stage 02

    Extract

    Fermentation yields the D-isomer only β€” the L-isomer is biologically inert. Purified to >98% before formulation.

  3. β—‡03

    Stage 03

    Assay

    HPLC-verified. β‰₯98% standardised for purity of pharmaceutical-grade d-panthenol.

  4. β—‰04

    Stage 04

    Formulate

    Effective 0.5%–5% in leave-in and rinse-off formulas.

  5. ⌘05

    Stage 05

    Deliver

    Stable 36 months in sealed formulas. Sealed under nitrogen where required.

07

Best for. Pairs with.

Best for

  • β—†Dry or dehydrated hair that feels brittle
  • β—†Fine hair needing lightweight moisture
  • β—†Anyone in dry indoor heating or A/C climates

Pairs well with

Hydrolyzed Keratin→Ceramide Complex→Glycerin→
08

In 4 formulas.

09

People often ask.

  • Is panthenol the same as B5?

    Panthenol is the pro-vitamin form β€” it converts to active B5 (pantothenic acid) once it's inside your hair or skin.

  • Does panthenol build up on hair?

    No β€” it's water-soluble and rinses cleanly. It's one of the few humectants that never causes residue.

10

The paper trail.

  • [01]Ebner F, et al. Am J Clin Dermatol. 2002 β€” Topical use of dexpanthenol in skin and hair disorders.

← Previous

Camellia Seed Oil

Camellia oleifera

Next β†’

Silk Amino Acids

Hydrolysed Bombyx mori Β· silk peptides

More in Vitamin

Continue the dossier.

Reveal
Your Inner
Shine
Editorial GHORI portrait